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  • Featured Product
  • KD/KO Validated

PTPIP51 Polyclonal antibody, PBS Only

PTPIP51 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 20641-1-PBS

Synonyms

FAM82A2, Protein FAM82A2, hucep-10, hRMD-3, hRMD 3

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PTPIP51 Polyclonal antibody (20641-1-AP)

    WB analysis using 20641-1-AP (same clone as 20641-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20641-1-AP (PTPIP51 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HEK-293 cells using PTPIP51 Polyclonal antibody (20641-1-AP)

    IP experiment of HEK-293 using 20641-1-AP (same clone as 20641-1-PBS)

    IP result of anti-PTPIP51 (IP:20641-1-AP, 4ug; Detection:20641-1-AP 1:1000) with HEK-293 cells lysate 1100ug. This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin tissue using PTPIP51 Polyclonal antibody (20641-1-AP)

    IHC staining of human skin using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin using 20641-1-AP (PTPIP51 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin tissue using PTPIP51 Polyclonal antibody (20641-1-AP)

    IHC staining of human skin using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human skin using 20641-1-AP (PTPIP51 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human paracancerous of skin cancer using PTPIP51 Polyclonal antibody (20641-1-AP)

    IHC staining of human paracancerous of skin cancer using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human paracancerous of skin cancer slide using 20641-1-AP (PTPIP51 antibody) at dilution of 1:600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using PTPIP51 Polyclonal antibody (20641-1-AP)

    IHC staining of human cervical cancer using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer using 20641-1-AP (PTPIP51 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using PTPIP51 Polyclonal antibody (20641-1-AP)

    IHC staining of human cervical cancer using 20641-1-AP (same clone as 20641-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer using 20641-1-AP (PTPIP51 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 20641-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

20641-1-PBS targets PTPIP51 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PTPIP51 fusion protein Ag14708 相同性解析による交差性が予測される生物種
Full Name family with sequence similarity 82, member A2
Calculated molecular weight 470 aa, 52 kDa
Observed molecular weight 52-60 kDa
GenBank accession numberBC008970
Gene symbol PTPIP51
Gene ID (NCBI) 55177
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Protein tyrosine phosphatase-interacting protein 51 (PTPIP51),also known as RMDN3, is a mitochondrial membrane-anchored protein that interacts with ER membrane-bound VAPB. The VAPB-PTPIP51 interaction impacts on intracellular Ca2+ handling (PMID: 22131369, 28345618). PTPIP51 participates in multiple cellular processes, and dysfunction of PTPIP51 is implicated in diseases such as cancer and neurodegenerative disorders (PMID: 28345618). The known initiation sites in the Ptpip51 gene would lead to molecular protein masses of 52, 38 and 30 kDa (PMID: 18854601,19844996).