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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PTPRS Polyclonal antibody (31720-1-AP)

    WB analysis using 31720-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of various lysates using PTPRS Polyclonal antibody (31720-1-AP)

    WB analysis using 31720-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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PTPRS Polyclonal antibody

PTPRS Polyclonal Antibody for WB, ELISA
Cat No. 31720-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

Receptor-type tyrosine-protein phosphatase sigma, Receptor-type tyrosine-protein phosphatase S, R PTP sigma, R PTP S, PTPSIGMA

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive WB detected inHEK-293 cells, A431 cells, HeLa cells, SH-SY5Y cells, mouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

31720-1-AP targets PTPRS in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name protein tyrosine phosphatase, receptor type, S
Calculated molecular weight217 kDa
Observed molecular weight140 kDa
GenBank accession numberNM_002850
Gene Symbol PTPRS
Gene ID (NCBI) 5802
RRIDAB_3670097
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
UNIPROT IDQ13332
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Protein tyrosine phosphatase receptor type S (PTPRS, also known as R-PTP-S, PTPSIGMA, and R-PTP-sigma) is an integral membrane protein. It can promote oligomerization by binding to large heparan sulfate proteoglycan structures, and interact with NTRK1/3, PPFIA1/2/3 (PMID: 25385546; 8524829; 9624153). The non-glycosylated molecular weight of PTPRS is 214 kDa, and the extracellular domain can be cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Variations and mutations of PTPRS are associated with Alzheimer's disease and cholangiocarcinoma (PMID: 38766183; 35991009).

Protocols

Product Specific Protocols
WB protocol for PTPRS antibody 31720-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols