Phospho-STK11/LKB1 (Thr189) Recombinant antibody, PBS Only
Phospho-STK11/LKB1 (Thr189) Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
5J9
Cat no : 80127-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
80127-1-PBS targets Phospho-STK11/LKB1 (Thr189) in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse samples.
Tested Reactivity | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
Full Name | serine/threonine kinase 11 |
Calculated molecular weight | 49 kDa |
Observed molecular weight | 50-55 kDa |
GenBank accession number | BC007981 |
Gene symbol | LKB1 |
Gene ID (NCBI) | 6794 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
STK11(serine/threonine-protein kinase 11) is also named as LKB1, PJS, and belongs to the protein kinase superfamily. It controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. The tumour suppressor protein LKB1 is a serine/threonine kinase that has been causally linked to Peutz-Jeghers syndrome (PJS). Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) and defects in STK11 have been associated with testicular germ cell tumor (TGCT) and some sporadic cancers, especially lung cancers.