Prohibitin Monoclonal antibody, PBS Only
Prohibitin Monoclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, pig, rat
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
4D3G5
Cat no : 60092-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60092-1-PBS targets Prohibitin in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig, rat samples.
Tested Reactivity | human, pig, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Prohibitin fusion protein Ag1240 相同性解析による交差性が予測される生物種 |
Full Name | prohibitin |
Calculated molecular weight | 30 kDa |
Observed molecular weight | 30 kDa |
GenBank accession number | BC013401 |
Gene symbol | Prohibitin |
Gene ID (NCBI) | 5245 |
RRID | AB_2252403 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis (PMID: 20840588 ). This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription (PMID: 18558096). Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis (PMID: 24402549).