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RAB27A Monoclonal antibody, PBS Only
RAB27A Monoclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1C4B8
Cat no : 66058-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66058-1-PBS targets RAB27A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | RAB27A fusion protein Ag12382 相同性解析による交差性が予測される生物種 |
Full Name | RAB27A, member RAS oncogene family |
Calculated molecular weight | 221 aa, 25 kDa |
Observed molecular weight | 27 kDa |
GenBank accession number | BC107680 |
Gene symbol | RAB27A |
Gene ID (NCBI) | 5873 |
RRID | AB_11042596 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Rab27A is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27A is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27A is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.