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RAD52 Monoclonal antibody, PBS Only

RAD52 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68283-1-PBS
Clone No.3H8G9

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

DNA repair protein RAD52 homolog, 3H8G9

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68283-1-PBS targets RAD52 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen RAD52 fusion protein Ag27665 相同性解析による交差性が予測される生物種
Full Name RAD52 homolog (S. cerevisiae)
Calculated molecular weight 46 aa
Observed molecular weight46 kDa
GenBank accession numberNM_001297419
Gene Symbol RAD52
Gene ID (NCBI) 5893
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP43351
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

In Saccharomyces cerevisiae, Rad52 functions as a critical mediator of homologous recombination (HR) by facilitating the loading of Rad51 onto ssDNA. However, in mammalian systems and other vertebrates, BRCA2 is known to function as the primary mediator of RAD51 filament formation, while prior studies have shown a limited role for RAD52 in HR.Additionally, loss of RAD52 has little consequence for cell viability. Recent evidence suggests that RAD52 may provide an alternative mediator pathway to BRCA2 function (PMID: 34928169). Several studies have suggested a link between the functional regulation of RAD52 and the protein modification by a small ubiquitin-like modifier (SUMO), sumoylation may play an important role in the nuclear transport of RAD52 (PMID:20190268). The calculated MW of Rad52 is 46 kDa, 68283-1-Ig can detect the band around 46 kDa.

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