Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66592-1-PBS targets RAF1 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | RAF1 fusion protein Ag25423 相同性解析による交差性が予測される生物種 |
Full Name | v-raf-1 murine leukemia viral oncogene homolog 1 |
Calculated molecular weight | 648 aa, 73 kDa |
Observed molecular weight | 70-75 kDa |
GenBank accession number | BC018119 |
Gene Symbol | RAF1 |
Gene ID (NCBI) | 5894 |
RRID | AB_2881952 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P04049 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Raf-1 proto-oncogene, serine/threonine kinase(RAF1), is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. RAF1 has two isoforms with MW of 73, 75 kDa. RAF1 plays an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.