RANK/TNFRSF11A Polyclonal antibody
RANK/TNFRSF11A Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 55293-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | MJ cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
55293-1-AP targets RANK/TNFRSF11A in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
Full Name | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
Calculated molecular weight | 66 kDa |
Observed molecular weight | 80-90 kDa |
GenBank accession number | NM_003839 |
Gene symbol | TNFRSF11A |
Gene ID (NCBI) | 8792 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK/RANKL/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470).
Protocols
Product Specific Protocols | |
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WB protocol for RANK/TNFRSF11A antibody 55293-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |