Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
13753-1-PBS targets RNASET2 in IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RNASET2 fusion protein Ag4695 相同性解析による交差性が予測される生物種 |
| Full Name | ribonuclease T2 |
| Calculated molecular weight | 256 aa, 29 kDa |
| Observed molecular weight | 29 kDa |
| GenBank accession number | BC039713 |
| Gene Symbol | RNase T2 |
| Gene ID (NCBI) | 8635 |
| RRID | AB_2285339 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O00584 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
RNASET2(Ribonuclease T2) is also named as RNASE6PL(Ribonuclease 6) and belongs to the RNase T2 family. It is a unique member of the growing family of tumor-antagonizing genes and behaves as a class II tumor suppressor and abolish the tumorigenic potential of an ovarian cancer-derived cell line. This protein has 2 isoforms produced by alternative splicing. Both mildly glycosylated (ranging from38 to 45 kDa) and highly glycosylated forms (ranging from 50 to 80 kDa) of human tumor suppressor protein RNASET2 can be detected in immunoblotting in P. Pastoris(PMID: 21446958).