- Featured Product
- KD/KO Validated
RND3 Monoclonal antibody, PBS Only
RND3 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, pig
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3H8F9
Cat no : 66228-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
66228-1-PBS targets RND3 in WB, Indirect ELISA applications and shows reactivity with human, pig samples.
| Tested Reactivity | human, pig |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | RND3 fusion protein Ag18839 相同性解析による交差性が予測される生物種 |
| Full Name | Rho family GTPase 3 |
| Calculated molecular weight | 244 aa, 27 kDa |
| Observed molecular weight | 29 kDa |
| GenBank accession number | BC012513 |
| Gene symbol | RND3 |
| Gene ID (NCBI) | 390 |
| RRID | AB_2881619 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.
