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RNF8 Monoclonal antibody, PBS Only

RNF8 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68521-1-PBS
Clone No.3G3H5

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, rabbit, pig

Applications

WB, Indirect ELISA

FLJ12013, KIAA0646, ring finger protein 8, RNF8

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68521-1-PBS targets RNF8 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit, pig samples.

Tested Reactivity Human, mouse, rat, rabbit, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen RNF8 fusion protein Ag5292 相同性解析による交差性が予測される生物種
Full Name ring finger protein 8
Calculated molecular weight 485 aa, 56 kDa
Observed molecular weight65-70 kDa
GenBank accession numberBC007517
Gene Symbol RNF8
Gene ID (NCBI) 9025
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO76064
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

RNF8, also named as KIAA0646 or E3 ubiquitin-protein ligase RNF8, is a 485 amino acid protein, which contains one RING-type zinc finger and one FHA domain. RNF8 localizes in the nucleus and belongs to the RNF8 family. E2-E3 ubiquitin ligase complex is composed of the RNF8 homodimer and a E2 heterodimer of UBE2N and UBE2V2. E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.

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