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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

ROR2 Monoclonal antibody, PBS Only

ROR2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A12C5

Cat no : 67906-1-PBS

Synonyms

BDB, BDB1, NTRKR2, ROR2

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using ROR2 Monoclonal antibody (67906-1-Ig)

    WB analysis using 67906-1-Ig (same clone as 67906-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67906-1-Ig (ROR2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 67906-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using ROR2 Monoclonal antibody (67906-1-Ig)

    WB analysis using 67906-1-Ig (same clone as 67906-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67906-1-Ig (ROR2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67906-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using ROR2 Monoclonal antibody (67906-1-Ig)

    WB analysis of NIH/3T3 using 67906-1-Ig (same clone as 67906-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67906-1-Ig (ROR2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67906-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67906-1-PBS targets ROR2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Reactivity Human, Mouse, Rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ROR2 fusion protein Ag31197 相同性解析による交差性が予測される生物種
Full Name receptor tyrosine kinase-like orphan receptor 2
Calculated molecular weight 943 aa, 105 kDa
Observed molecular weight105 kDa
GenBank accession numberBC130522
Gene symbol ROR2
Gene ID (NCBI) 4920
RRIDAB_2918662
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Tyrosine-protein kinase transmembrane receptor ROR2 belongs to the ROR family of receptor tyrosine kinases (RTKs) (PMID: 12815588). ROR2 is a developmentally regulated protein that has significant expression and roles in a wide variety of tissues during early embryonic development. It was established that ROR2 plays a key role in skeletal and neural organogenesis, as well as in midgut development in the mouse, but then becomes repressed in adult tissues. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PMID: 25614331). Mutations in the ROR2 gene are associated with autosomal recessive Robinow syndrome and autosomal dominant brachydactyly type B (PMID: 12815588).