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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
84670-3-PBS targets RPL11 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | RPL11 fusion protein Ag9356 相同性解析による交差性が予測される生物種 |
| Full Name | ribosomal protein L11 |
| Calculated molecular weight | 177 aa, 20 kDa |
| Observed molecular weight | 20 kDa |
| GenBank accession number | BC018970 |
| Gene Symbol | RPL11 |
| Gene ID (NCBI) | 6135 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | P62913 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Ribosomal protein L11 is one of 80 mammalian ribosome proteins. It can bind to 5S ribosomal RNA, for it's required for rRNA maturation and formation of the 60S ribosomal subunit. It can inhibit 40S or 60S ribosome biogenesis via mediated p53 induction. Once retained by PICT1 in the nucleolus, RPL11 involve in regulation of the MDM2-P53 pathway and promotion of tumor progression.