SAP 97 Polyclonal antibody

SAP 97 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 55085-1-AP

Synonyms

Disks large homolog 1, DLG1, DLGH1, hdlg, SAP 97, SAP97, Synapse associated protein 97


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Tested Applications

Positive WB detected inmouse lung tissue, HeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55085-1-AP targets SAP 97 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, rat, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name discs, large homolog 1 (Drosophila)
Calculated molecular weight 100 kDa
Observed molecular weight 120 kDa, 130-140 kDa
GenBank accession numberNM_004087
Gene symbol SAP97
Gene ID (NCBI) 1739
RRIDAB_11182375
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer 0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

DLG1, also naemd as SAP97, hDlg and DLGH1, belongs to the MAGUK family. It is essential multidomain scaffolding protein required for normal development. DLG1 may play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. It regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. DLG1 is a functional regulator of Kv1.5 channel. The DLG1-MPP7 complex promotes epithelial cell polarity and tight junction formation. The antibody is specific to DLG1.

Protocols

Product Specific Protocols
WB protocol for SAP 97 antibody 55085-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse, humanIF

Kidney Int

Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney.

Authors - Rik Westland
ratWB

Neurochem Res

PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model

Authors - Jiawei Yang