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Species Reactivity
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Conjugate
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Conjugate
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Conjugate
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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

SCN3B Recombinant antibody, PBS Only

SCN3B Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, rat, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230316F8

Cat no : 82959-1-PBS

Synonyms

Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using SCN3B Recombinant antibody (82959-1-RR)

    WB analysis using 82959-1-RR (same clone as 82959-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82959-1-RR (SCN3B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82959-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82959-1-PBS

    Affinity and Kinetic Characterization of 82959-1-PBS

    Biolayer interferometry (BLl) kinetic assays of 82959-1-RR against Human SCN3B were performed. The affinity constant is 0.429 nM.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

82959-1-PBS targets SCN3B in WB, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Reactivity Human, rat, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen SCN3B fusion protein Ag23201 相同性解析による交差性が予測される生物種
Full Name sodium channel, voltage-gated, type III, beta
Observed molecular weight29 kDa
GenBank accession numberBC126265
Gene symbol SCN3B
Gene ID (NCBI) 55800
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The sodium voltage-gated channel beta subunit 3 (SCN3B) plays a crucial role in electrically excitable cells and conduction tissue in the heart. Some previous studies have established that genetic modification in sodium voltage-channel genes encoding for the cardiac β-subunits, such as SCN1B, SCN2B, SCN3B and SCN4B, can result in atrial fibrillation (AF). (PMID: 36362949)