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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

SERPINB9 Polyclonal antibody

SERPINB9 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 14910-1-AP

Synonyms

CAP 3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI 9, PI9, Serpin B9, SERPINB9

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using SERPINB9 Polyclonal antibody (14910-1-AP)

    WB analysis using 14910-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 14910-1-AP (SERPINB9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inK-562 cells, Human placenta tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14910-1-AP targets SERPINB9 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SERPINB9 fusion protein Ag6707 相同性解析による交差性が予測される生物種
Full Name serpin peptidase inhibitor, clade B (ovalbumin), member 9
Calculated molecular weight 42 kDa
Observed molecular weight 42 kDa
GenBank accession numberBC002538
Gene symbol SERPINB9
Gene ID (NCBI) 5272
RRIDAB_2254462
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SERPINB9, also named as PI-9, belongs to the serpin family. SERPINB9 is an intracellular inhibitor of granzyme B (grB) that protects cytotoxic lymphocytes from grB-mediated death. It has a nucleo-cytoplasmic distribution and is produced in CD8+ T cells and natural killer cells (PMID: 28024184). Also, SERPINB9 is expressed by vascular SMCs and endothelial cells to avoid GZB-induced apoptosis (PMID: 28743062). The molecular weight of SERPINB9 is 42 kDa.

Protocols

Product Specific Protocols
WB protocol for SERPINB9 antibody 14910-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols