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  • KD/KO Validated

SERPINE2 Polyclonal antibody

SERPINE2 Polyclonal Antibody for WB, IHC, IF-P, IP, ELISA
Cat No. 11303-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF-P, IP, ELISA

PI7, PN1, Serpin E2, PI 7, Peptidase inhibitor 7

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inC6 cells, A549 cells, MCF-7 cells, rat brain tissue, rat heart tissue
Positive IP detected inA549 cells
Positive IHC detected inhuman testis tissue, human pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF-P detected inhuman testis tissue, mouse testis tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11303-1-AP targets SERPINE2 in WB, IHC, IF-P, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SERPINE2 fusion protein Ag1830 相同性解析による交差性が予測される生物種
Full Name serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Calculated molecular weight 44 kDa
Observed molecular weight 44-50 kDa
GenBank accession numberBC015663
Gene Symbol SERPINE2
Gene ID (NCBI) 5270
RRIDAB_10732939
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP07093
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SERPINE2 also called protease nexin-1 or glial-derived neurite promoting factor, is a member of the serine protease inhibitor (SERPIN) superfamily. It would be a potent inhibitor of the urokinase-plasminogen activator (uPA), tissue-type PA (tPA), thrombin, trypsin, factor Xia, and prostasin. SERPINE2 is widely expressed in various tissues, including endothelial cells, fibroblasts, smooth muscle cells, tumor cells, glial cells, neurons, and placental cells.

Protocols

Product Specific Protocols
WB protocol for SERPINE2 antibody 11303-1-APDownload protocol
IHC protocol for SERPINE2 antibody 11303-1-APDownload protocol
IF protocol for SERPINE2 antibody 11303-1-APDownload protocol
IP protocol for SERPINE2 antibody 11303-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC,IP

Cancer Lett

SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer.

Authors - Jingjing Zhang
  • KD Validated
humanWB,IHC

Respir Res

High expression level of serpin peptidase inhibitor clade E member 2 is associated with poor prognosis in lung adenocarcinoma.

Authors - Ryota Dokuni
  • KD Validated
humanWB

J Immunol

Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human Synoviocytes.

Authors - Shengquan Tang
humanIP

Front Cell Dev Biol

BAP31 Promotes Tumor Cell Proliferation by Stabilizing SERPINE2 in Hepatocellular Carcinoma.

Authors - Xiyang Zhang
mouseIF

Sci Rep

PMID: 30446696

Authors - Mary Ann Stepp
humanIHC

J Cell Physiol

Transcriptional profiling of endometriosis tissues identifies genes related to organogenesis defects.

Authors - Crispi Stefania S
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