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- KD/KO Validated
SGOL1 Polyclonal antibody
SGOL1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
Cat no : 16977-1-AP
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | HeLa cells, PC-3 cells, NIH/3T3 cells, mouse heart tissue, rat heart tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 2 publications below |
| WB | See 4 publications below |
| IHC | See 4 publications below |
| IF | See 2 publications below |
Product Information
16977-1-AP targets SGOL1 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SGOL1 fusion protein Ag9700 相同性解析による交差性が予測される生物種 |
| Full Name | shugoshin-like 1 (S. pombe) |
| Calculated molecular weight | 561aa,64 kDa; 292aa,34 kDa |
| Observed molecular weight | 64 kDa |
| GenBank accession number | BC017867 |
| Gene symbol | SGOL1 |
| Gene ID (NCBI) | 151648 |
| RRID | AB_2188437 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SGOL1 (Shugoshin 1), a centromeric protein, plays an important role in mitosis (PMID: 23102702).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for SGOL1 antibody 16977-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Carcinogenesis Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice. | ||
Front Oncol Deciphering the Role of Shugoshin-Like Protein 1 in Lung Adenocarcinoma: A Comprehensive Analysis and In Vitro Study. | ||
Mol Carcinog Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model. | ||
BMC Med Genomics Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis
| ||
Front Oncol Identification and validation of a potential key gene SGOL1 for poor prognosis in hepatocellular carcinoma based on a bioinformatics approach | ||
J Mol Cell Biol Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis
|
