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Validation Data Gallery

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  • Western Blot (WB) analysis of mouse thymus tissue using SH2D1A Polyclonal antibody (11868-1-AP)

    WB analysis of mouse thymus using 11868-1-AP

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

［PR］まずは試したいあなたに。トライアルサイズも特別価格 >>『PRIME BUY抗体特割キャンペーン（4/21～）』

SH2D1A Polyclonal antibody

SH2D1A Polyclonal Antibody for WB, ELISA
Cat No. 11868-1-AP
Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

DSHP, Duncan disease SH2 protein, EBVS, IMD5, LYP, MTCP1, SAP, SH2 domain protein 1A, SH2D1A, SLAM associated protein, XLP, XLPD

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

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テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive WB detected inmouse thymus tissue, Jurkat cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

11868-1-AP targets SH2D1A in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SH2D1A fusion protein Ag2450 相同性解析による交差性が予測される生物種
Full Name SH2 domain protein 1A
Calculated molecular weight 128 aa, 14 kDa
Observed molecular weight 16 kDa
GenBank accession numberBC020732
Gene Symbol SH2D1A
Gene ID (NCBI) 4068
RRIDAB_2239283
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO60880
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SH2D1A, also named as DSHP and SAP, is an inhibitor of the SLAM self-association. It acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. SH2D1A mediates interaction between FYN and SLAMF1. Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1).

Protocols

Product Specific Protocols
WB protocol for SH2D1A antibody 11868-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Arthritis Rheum

Decreased microRNA-142-3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus.

Authors - Ding Shu S
View Article