SHC1 Monoclonal antibody, PBS Only (Capture)
SHC1 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
WB, Cytometric bead array, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A5B1
Cat no : 67194-2-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67194-2-PBS targets SHC1 as part of a matched antibody pair:
MP50763-1: 67194-2-PBS capture and 67194-3-PBS detection (validated in Cytometric bead array)
MP50763-3: 67194-2-PBS capture and 67194-4-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | SHC1 fusion protein Ag25173 相同性解析による交差性が予測される生物種 |
| Full Name | SHC (Src homology 2 domain containing) transforming protein 1 |
| Calculated molecular weight | 63 kDa |
| Observed molecular weight | 66 kDa |
| GenBank accession number | NM_183001 |
| Gene symbol | SHC1 |
| Gene ID (NCBI) | 6464 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
The proto-oncogene SHC family consists of SHCA, SHCB, SHCC, and SHCD4 gene members, which can encode 7 kinds of cohesive molecules. SHC family is widely expressed and functional. The SHC1 gene is located in zone 1, region 2 of human chromosome 1. SHC1 is believed to be involved in inhibiting neuronal apoptosis and regulating the receptor tyrosine kinase pathway. SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.
