SLC17A5 Polyclonal antibody, PBS Only
SLC17A5 Polyclonal Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
Cat no : 13320-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
13320-1-PBS targets SLC17A5 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | SLC17A5 fusion protein Ag3855 相同性解析による交差性が予測される生物種 |
Full Name | solute carrier family 17 (anion/sugar transporter), member 5 |
Calculated molecular weight | 495 aa, 55 kDa |
Observed molecular weight | 31 kDa |
GenBank accession number | BC020961 |
Gene symbol | SLC17A5 |
Gene ID (NCBI) | 26503 |
RRID | AB_2187524 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
SLC17A5 encodes a transmembrane protein, sialin, which transports free sialic acid across the lysosomal membrane. Mutations in sialin result in neurodegenerative sialic acid storage disorders, Salla disease (SD) and infantile sialic acid storage disease (ISSD). In the central nervous system, sialin is more abundant in neurons than in glia. It has been reported to be localized into lysosome in neuron but in plasma membrane in nonneuronal cells (PMID: 15006695).