SLC25A1 Monoclonal antibody, PBS Only
SLC25A1 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG3
Reactivity
Human, Mouse, Rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1F11A3
Cat no : 66771-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66771-1-PBS targets SLC25A1 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse / IgG3 |
Class | Monoclonal |
Type | Antibody |
Immunogen | SLC25A1 fusion protein Ag7520 相同性解析による交差性が予測される生物種 |
Full Name | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
Calculated molecular weight | 34 kDa |
Observed molecular weight | 34 kDa |
GenBank accession number | BC004980 |
Gene symbol | SLC25A1 |
Gene ID (NCBI) | 6576 |
RRID | AB_2882117 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 has been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. This antibody specifically recognized the endogenous SLC25A1; no protein was detected in cells from subjects containing two alleles with truncating mutations with this antibody. (24681808, 23561848)