SLC37A2 Polyclonal antibody

SLC37A2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 20469-1-AP

Synonyms

pp11662, SLC37A2, SPX2, Sugar phosphate exchanger 2


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Tested Applications

Positive WB detected inmouse thymus tissue, HeLa cells, RAW 264.7 cells, mouse spleen tissue, rat thymus tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:300-1:600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

20469-1-AP targets SLC37A2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SLC37A2 fusion protein Ag14306 相同性解析による交差性が予測される生物種
Full Name solute carrier family 37 (glycerol-3-phosphate transporter), member 2
Calculated molecular weight 505 aa, 55 kDa
Observed molecular weight 50-75 kDa
GenBank accession numberBC051314
Gene symbol SLC37A2
Gene ID (NCBI) 219855
RRIDAB_10733754
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The solute carrier family 37 (SLC37) consists of four sugar-phosphate exchangers, A1, A2, A3, and A4, which are anchored in the endoplasmic reticulum (ER) membrane (PMID:23506893). Solute Carrier Family 37 Member 2 (SLC37A2), also knows as SPX2, was firstly identified in a work, conducted on mice and aimed to detect cAMP inducible genes playing a role in promoting cholesterol efflux from the macrophage cell line RAW264 via apoE and apoA1 (PMID:11004510). Interestingly, of the four SLC37A members, SLC37A2 displays the highest level of transcript abundance in neutrophils and macrophages ,indicating that SLC37A2 may play an essential role in regulating innate immune function (PMID:32428862).

Protocols

Product Specific Protocols
WB protocol for SLC37A2 antibody 20469-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC

Cell Biol Toxicol

hucMSC-Ex alleviates inflammatory bowel disease in mice by enhancing M2-type macrophage polarization via the METTL3-Slc37a2-YTHDF1 axis

Authors - Xinwei Xu