- Featured Product
- KD/KO Validated
SMN (Human-Specific) Monoclonal antibody, PBS Only
SMN (Human-Specific) Monoclonal Antibody for WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2C6D9
Cat no : 60154-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60154-1-PBS targets SMN (Human-Specific) in WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | SMN (Human-Specific) fusion protein Ag14333 相同性解析による交差性が予測される生物種 |
Full Name | survival of motor neuron 2, centromeric |
Calculated molecular weight | 282 aa, 30 kDa |
Observed molecular weight | 38 kDa |
GenBank accession number | BC000908 |
Gene symbol | SMN |
Gene ID (NCBI) | 6607 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The survival of motor neurons (SMN) genes are the disease genes of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody 60154-1-Ig is specific to human SMN2. It can't recognize mouse and rat SMN.