Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
83771-5-PBS targets SMUG1 in WB, FC (Intra), ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | SMUG1 fusion protein Ag13934 相同性解析による交差性が予測される生物種 |
Full Name | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
Calculated molecular weight | 177 aa, 20 kDa |
Observed molecular weight | 30 kDa |
GenBank accession number | BC000417 |
Gene Symbol | SMUG1 |
Gene ID (NCBI) | 23583 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q53HV7 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
UNG(Uracil-DNA glycosylase) removes uracil in DNA resulting from deamination of cytosine or replicative incorporation of dUMP instead of dTMP. Thus, UNG plays a role in suppressing GC-to-AT transition mutations.The UNG gene encodes 2 isoforms that are individually targeted to the mitochondria and the nucleus(PMID:12369930).Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5).