Validation Data Gallery
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Tested Applications
| Positive WB detected in | BGC-823 cells, NCI-H1299 cells |
| Positive IP detected in | SH-SY5Y cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 3 publications below |
| WB | See 5 publications below |
| IHC | See 2 publications below |
| IF | See 2 publications below |
| ChIP | See 1 publications below |
Product Information
18902-1-AP targets SOX13 in WB, IHC, IF, IP, chIP, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SOX13 fusion protein Ag13537 相同性解析による交差性が予測される生物種 |
| Full Name | SRY (sex determining region Y)-box 13 |
| Calculated molecular weight | 622 aa, 69 kDa |
| Observed molecular weight | 69 kDa |
| GenBank accession number | BC106038 |
| Gene Symbol | SOX13 |
| Gene ID (NCBI) | 9580 |
| RRID | AB_10642149 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UN79 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SRY-BOX 13(SOX13), identified a sequence homologous more than 60% to the SRY HMG box ,with a centrally located HMG box and an N-terminal leucine zipper motif with a neighboring glutamine stretch called a Q box. SOX13 binds to the consensus HMG-box motif. It's an IDDM-specific human autoantigen, and a gamma-delta-specific gene in the immune system. It can modulates Wnt/TCF activity. This is a rabbit polyclonal raised against part of N-terminal chain of SOX13 of human origin.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for SOX13 antibody 18902-1-AP | Download protocol |
| IP protocol for SOX13 antibody 18902-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Front Cardiovasc Med Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells
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Lab Invest Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
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Mol Cell Biochem Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development. | ||
Bioengineered Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.
| ||
J Exp Clin Cancer Res FUS/circ_002136/miR-138-5p/SOX13 feedback loop regulates angiogenesis in Glioma. |