☆ 3/31(月)まで!二次抗体 & FlexAbleが30%オフ! >> 免疫アッセイサポートキャンペーン

SUR1 Polyclonal antibody, PBS Only

SUR1 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 55172-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。


国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

55172-1-PBS targets SUR1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Calculated molecular weight 177 kDa
Observed molecular weight140–177 kDa
GenBank accession numberNM_000352
Gene Symbol SUR1
Gene ID (NCBI) 6833
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ09428
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

SUR1 (Sulfonylurea receptor 1) is a member of the adenosine triphosphate (ATP)-binding cassette (ABC) protein superfamily, which encompasses a large group of membrane proteins that regulate the transport of ions and molecules across lipid bilayers (PMID:34769328). SUR1 regulates ATP-sensitive K+ channels and insulin release. Loss-of-function SUR1 mutations cause congenital hyperinsulinism and gain-of-function SUR1 mutations leading to neonatal diabetes (PMID: 18990670). SUR1 is recognized as a key mediator of central nervous system cellular swelling by the transient receptor potential melastatin 4 (TRPM4) channel. SUR1 (Sulfonylurea receptor 1) is a member of the adenosine triphosphate (ATP)-binding cassette (ABC) protein superfamily, which encompasses a large group of membrane proteins that regulate the transport of ions and molecules across lipid bilayers (PMID:34769328). SUR1 regulates ATP-sensitive K+ channels and insulin release. Loss-of-function SUR1 mutations cause congenital hyperinsulinism and gain-of-function SUR1 mutations leading to neonatal diabetes (PMID: 18990670). SUR1 is recognized as a key mediator of central nervous system cellular swelling by the transient receptor potential melastatin 4 (TRPM4) channel. SUR1 was detected 140-177 kDa in the pancreas, brain, heart (PMID: 34380876).

Loading...