TAX1BP1 Monoclonal antibody, PBS Only
TAX1BP1 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1H2D10
Cat no : 60466-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60466-1-PBS targets TAX1BP1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TAX1BP1 fusion protein Ag6279 相同性解析による交差性が予測される生物種 |
Full Name | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
Calculated molecular weight | 91 kDa |
Observed molecular weight | 68 kDa, 85 kDa |
GenBank accession number | BC050358 |
Gene symbol | TAX1BP1 |
Gene ID (NCBI) | 8887 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.