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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

TERF1 Monoclonal antibody, PBS Only

TERF1 Monoclonal Antibody for Indirect ELISA, WB

Host / Isotype

Mouse / IgG1

Reactivity

rat, mouse, human

Applications

Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

1D10G4

Cat no : 67592-1-PBS

Synonyms

Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS

Validation Data Gallery

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  • Western Blot (WB) analysis of K-562 cells using TERF1 Monoclonal antibody (67592-1-Ig)

    WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using TERF1 Monoclonal antibody (67592-1-Ig)

    WB analysis of HEK-293 using 67592-1-Ig (same clone as 67592-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using TERF1 Monoclonal antibody (67592-1-Ig)

    WB analysis of Jurkat using 67592-1-Ig (same clone as 67592-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67592-1-PBS targets TERF1 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.

Tested Reactivity rat, mouse, human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TERF1 fusion protein Ag12540 相同性解析による交差性が予測される生物種
Full Name telomeric repeat binding factor (NIMA-interacting) 1
Calculated molecular weight 439 aa, 50 kDa
Observed molecular weight 48-50 kDa
GenBank accession numberBC029378
Gene symbol TERF1
Gene ID (NCBI) 7013
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.