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  • KD/KO Validated

TEX10 Polyclonal antibody

TEX10 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, IP, ELISA

Conjugate

Unconjugated

Cat no : 17372-1-AP

Synonyms

Testis-expressed protein 10, testis expressed 10, Nbla10363, L18


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Tested Applications

Positive WB detected inHeLa cells
Positive IHC detected inhuman brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)/ICCIF/ICC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17372-1-AP targets TEX10 in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TEX10 fusion protein Ag11014 相同性解析による交差性が予測される生物種
Full Name testis expressed 10
Calculated molecular weight 929 aa, 106 kDa
Observed molecular weight 95-100 kDa
GenBank accession numberBC030652
Gene symbol TEX10
Gene ID (NCBI) 54881
RRIDAB_2201871
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TEX10 is a component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5. PELP1-TEX10-WDR18 complex is a regulator of ribosome biogenesis and suggests that its SUMO-controlled distribution coordinates the rate of ribosome formation. And this complex is required for the maturation and nucleolar release of the large ribosomal subunit. (PMID:21326211)

Protocols

Product Specific Protocols
WB protocol for TEX10 antibody 17372-1-APDownload protocol
IHC protocol for TEX10 antibody 17372-1-APDownload protocol
IF protocol for TEX10 antibody 17372-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IF

EMBO J

The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex.

Authors - Finkbeiner Elisabeth E
  • KD Validated
humanWB

Mol Cell Proteomics

Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.

Authors - Fanis Pavlos P
humanWB,IHC,IF

Cell Cycle

Tex10 is upregulated and promotes cancer stem cell properties and chemoresistance in hepatocellular carcinoma.

Authors - Xiaocong Xiang
  • KD Validated
humanWB,IF

Mol Biol Cell

LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis.

Authors - Castle Christopher D CD
humanWB

J Immunol Res

TEX10 Promotes the Tumorigenesis and Radiotherapy Resistance of Urinary Bladder Carcinoma by Stabilizing XRCC6

Authors - Sheng Luo
  • KD Validated
humanWB,IHC

Oncol Rep

Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β‑catenin pathway.

Authors - Xiaocong Xiang
  • KD Validated