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- KD/KO Validated
TGFBR2 Monoclonal antibody, PBS Only
TGFBR2 Monoclonal Antibody for WB, IHC, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse , Rat
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
2D5H7
Cat no : 66636-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66636-1-PBS targets TGFBR2 in WB, IHC, ELISA applications and shows reactivity with Human, Mouse , Rat samples.
Tested Reactivity | Human, Mouse , Rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TGFBR2 fusion protein Ag25773 相同性解析による交差性が予測される生物種 |
Full Name | transforming growth factor, beta receptor II (70/80kDa) |
Calculated molecular weight | 65 kDa |
Observed molecular weight | 65-80 kDa |
GenBank accession number | BC040499 |
Gene symbol | TGFBR2 |
Gene ID (NCBI) | 7048 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
TGF beta Receptor II (TGFBR2) is a member of the transforming growth factor-β (TGF-β) superfamily, which are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis (PMID: 10974075). TGFBR2 result in both SMAD4-dependent constraint of proliferation and SMAD4-independent activation of apoptosis (PMID: 29396446). It has some isoforms with the molecular weight of 70-80 kDa and ~90 kDa after glycosylated.