TIMELESS Monoclonal antibody, PBS Only
TIMELESS Monoclonal Antibody for Indirect ELISA, WB
Host / Isotype
Mouse / IgG1
Reactivity
rat, mouse, human
Applications
Indirect ELISA, WB
Conjugate
Unconjugated
CloneNo.
1B6G3
Cat no : 67022-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67022-1-PBS targets TIMELESS in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.
Tested Reactivity | rat, mouse, human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TIMELESS fusion protein Ag6283 相同性解析による交差性が予測される生物種 |
Full Name | timeless homolog (Drosophila) |
Calculated molecular weight | 139 kDa |
Observed molecular weight | 140 kDa |
GenBank accession number | BC050557 |
Gene symbol | TIMELESS |
Gene ID (NCBI) | 8914 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
TIMELESS1 (TIM1) gene encodes protein timeless homolog belonging to timeless family. TIM1 is localized in nucleus and regulated by cell cycle. It expresses high levels in S, G2 and M phases, and low in G0 and G1 phases. TIM1 is involved in the circadian rhythm autoregulatory loop and is a crucial component of the circadian core oscillator, which includes the CRY proteins, CLOCK, NPAS2, etc. It is also involved in cell survival after DNA damage or replication stress and reported to play important role in epithelial cell morphogenesis and formation of branching tubules.