TMBIM6 Polyclonal antibody

TMBIM6 Polyclonal Antibody for WB, IP, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF, IP, ELISA

Conjugate

Unconjugated

Cat no : 26782-1-AP

Synonyms

Bax inhibitor 1, BAXI1, BI 1, BI1, TEGT, TMBIM6


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Tested Applications

Positive WB detected inmouse liver tissue
Positive IP detected inmouse testis tissue
Positive IHC detected inhuman testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 26782-1-AP is TMBIM6 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TMBIM6 fusion protein Ag24780 相同性解析による交差性が予測される生物種
Full Name transmembrane BAX inhibitor motif containing 6
Calculated molecular weight 27 kDa
Observed molecular weight 27 kDa
GenBank accession numberBC000916
Gene symbol TMBIM6
Gene ID (NCBI) 7009
RRIDAB_2880633
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for TMBIM6 antibody 26782-1-APDownload protocol
IHC protocol for TMBIM6 antibody 26782-1-APDownload protocol
IP protocol for TMBIM6 antibody 26782-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

J Cell Physiol

Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.

Authors - Lina Wu
human,mouseWB,IHC,IF

Mol Biol Rep

TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.

Authors - Huidi Xie
mouseWB

Life Sci Alliance

The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth

Authors - Marina Badenes
humanWB,IHC

Mol Med

Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner

Authors - Yangyang Chen
humanWB,IF

Eur J Med Chem

13-oxyingenol dodecanoate derivatives induce mitophagy and ferroptosis through targeting TMBIM6 as potential anti-NSCLC agents

Authors - Yaxu Wang
humanWB

J Cancer

LncRNA SNHG1 acts as a ceRNA for miR-216a-3p to regulate TMBIM6 expression in esophageal squamous cell carcinoma

Authors - Ni Kong