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Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using TNFRSF13C Polyclonal antibody (22582-1-AP)

    IHC staining of human tonsillitis using 22582-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22582-1-AP (TNFRSF13C Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using TNFRSF13C Polyclonal antibody (22582-1-AP)

    IHC staining of human tonsillitis using 22582-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22582-1-AP (TNFRSF13C Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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CD268/BAFF-R Polyclonal antibody

CD268/BAFF-R Polyclonal Antibody for IHC, ELISA
Cat No. 22582-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Synonyms

TNFRSF13C, BLyS receptor 3, B-cell-activating factor receptor, BAFF-R, BAFFR

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

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約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

22582-1-AP targets CD268/BAFF-R in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CD268/BAFF-R fusion protein Ag18202 相同性解析による交差性が予測される生物種
Full Name tumor necrosis factor receptor superfamily, member 13C
Calculated molecular weight 184 aa, 19 kDa
GenBank accession numberBC105123
Gene Symbol TNFRSF13C
Gene ID (NCBI) 115650
RRIDAB_2879126
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ96RJ3
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).

Protocols

Product Specific Protocols
IHC protocol for CD268/BAFF-R antibody 22582-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols