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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CD268/BAFF-R Recombinant antibody, PBS Only (Capture)

CD268/BAFF-R Recombinant Antibody for Sandwich ELISA, Indirect ELISA, Sample test

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Sandwich ELISA, Indirect ELISA, Sample test

Conjugate

Unconjugated

CloneNo.

242003C5

Cat no : 84585-4-PBS

Synonyms

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

Validation Data Gallery

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  • Sandwich ELISA standard curve of MP01419-3

    Sandwich ELISA standard curve of MP01419-3

    Sandwich ELISA standard curve of MP01419-3, Human TNFRSF13C Recombinant Matched Antibody Pair - PBS only. 84585-4-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg1922. 84585-3-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL.

  • Sample test of MP01419-3

    Sample test of MP01419-3

    Serum of six individual healthy human donors was measured. The TNFRSF13C concentration of detected samples was determined to be 0.64 ng/mL with a range of 0.27-0.85 ng/mL.

  • Affinity and Kinetic Characterization of 84585-4-PBS

    Affinity and Kinetic Characterization of 84585-4-PBS

    Biolayer interferometry (BLl) kinetic assay of 84585-4-PBS against Human TNFRSF13C was performed. The affinity constant is 3.96 nM.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

84585-4-PBS targets CD268/BAFF-R as part of a matched antibody pair:

MP01419-3: 84585-4-PBS capture and 84585-3-PBS detection (validated in Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name tumor necrosis factor receptor superfamily, member 13C
Calculated molecular weight 184 aa, 19 kDa
GenBank accession numberBC105123
Gene symbol TNFRSF13C
Gene ID (NCBI) 115650
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).