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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

TRIM26 Recombinant antibody

TRIM26 Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

242154B5

Cat no : 84661-4-RR

Synonyms

ZNF173, Tripartite motif-containing protein 26, TRIM, RNF95, EC:2.3.2.27

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TRIM26 Recombinant antibody (84661-4-RR)

    WB analysis using 84661-4-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 84661-4-RR (TRIM26 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inHeLa cells, HepG2 cells, Jurkat cells, HEK-293T cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

84661-4-RR targets TRIM26 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TRIM26 fusion protein Ag25546 相同性解析による交差性が予測される生物種
Full Name tripartite motif-containing 26
Calculated molecular weight 62 kDa
Observed molecular weight 60-70 kDa
GenBank accession numberBC024039
Gene symbol TRIM26
Gene ID (NCBI) 7726
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation. (PMID: 25763818, PMID: 26611359)

Protocols

Product Specific Protocols
WB protocol for TRIM26 antibody 84661-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols