TRPV2 Polyclonal antibody

TRPV2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 15991-1-AP

Synonyms

Osm 9 like TRP channel 2, OTRPC2, TRPV2, VRL, VRL 1, VRL1


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Tested Applications

Positive WB detected inJurkat cells, K-562 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 1 publications below

Product Information

15991-1-AP targets TRPV2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRPV2 fusion protein Ag8864 相同性解析による交差性が予測される生物種
Full Name transient receptor potential cation channel, subfamily V, member 2
Calculated molecular weight 764 aa, 86 kDa
Observed molecular weight90 kDa
GenBank accession numberBC018926
Gene symbol TRPV2
Gene ID (NCBI) 51393
RRIDAB_3085477
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Transient receptor potential vanilloid 2 (TRPV2), also name as VRL-1, plays a critical role in neuronal development, cardiac function, immunity, and cancer (PMID: 31566564). It has been found to play an essential role in sustained intracellular Ca2+ concentration increase (PMID: 31857697). It's reported that TRPV2 is activated by high temperatures, with a threshold of around 52℃ (PMID: 10201375). The calculated molecular of TRPV2 is 86 kDa, 15991-1-AP can detect the band around 90 kDa.

Protocols

Product Specific Protocols
WB protocol for TRPV2 antibody 15991-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

EMBO Mol Med

Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.

Authors - Yi Huang