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TRPV6 Polyclonal antibody

TRPV6 Polyclonal Antibody for WB, IF/ICC, IP, ELISA
Cat No. 13411-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IF/ICC, IP, ELISA

CATL, CaT1, CaT like, CaT L, Calcium transport protein 1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inhuman placenta tissue, mouse kidney tissue, PC-3 cells
Positive IP detected inmouse kidney tissue
Positive IF/ICC detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13411-1-AP targets TRPV6 in WB, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRPV6 fusion protein Ag4060 相同性解析による交差性が予測される生物種
Full Name transient receptor potential cation channel, subfamily V, member 6
Calculated molecular weight 725 aa, 83 kDa
Observed molecular weight 83 kDa, 70 kDa
GenBank accession numberBC034814
Gene Symbol TRPV6
Gene ID (NCBI) 55503
RRIDAB_2272390
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9H1D0
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.

Protocols

Product Specific Protocols
WB protocol for TRPV6 antibody 13411-1-APDownload protocol
IF protocol for TRPV6 antibody 13411-1-APDownload protocol
IP protocol for TRPV6 antibody 13411-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

J Mol Cell Cardiol

TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.

Authors - Zhichao Li
humanIF

iScience

A microengineered Brain-Chip to model neuroinflammation in humans

Authors - Iosif Pediaditakis
humanWB,IF

Mol Cancer Res

PMID: 19996302

Authors - Bolanz Katrin A KA
mouseWB

Front Pharmacol

Aqueous Extract of Mori Folium Exerts Bone Protective Effect Through Regulation of Calcium and Redox Homeostasis via PTH/VDR/CaBP and AGEs/RAGE/Nox4/NF-κB Signaling in Diabetic Rats.

Authors - Chenyue Liu
humanWB

J Gastroenterol Hepatol

Vitamin D receptor is overexpressed in the duodenum of patients with irritable bowel syndrome.

Authors - Ko Miura
mouseWB

Mol Reprod Dev

Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.

Authors - Yu Lin
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