TTBK2 Recombinant antibody, PBS Only
TTBK2 Recombinant Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
241456B4
Cat no : 84634-1-PBS
Synonyms
Validation Data Gallery
Filter:
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
The immunogen of 84634-1-PBS is TTBK2 Fusion Protein expressed in E. coli.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | TTBK2 fusion protein Ag7108 相同性解析による交差性が予測される生物種 |
| Full Name | tau tubulin kinase 2 |
| Calculated molecular weight | 137 kDa |
| Observed molecular weight | 137-150 kDa |
| GenBank accession number | BC071556 |
| Gene symbol | TTBK2 |
| Gene ID (NCBI) | 146057 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
TTBK2(tau tubulin kinase 2) plays an important role in the tau cascade and in spinocerebellar degeneration. The N-terminus of TTBK2 has a serine-threonine-tyrosine kinase domain, and a C-terminal region shows homology to TTBK1. TTBK1 and TTBK2 function as regulators of TDP-43 phosphorylation. TTBK1/2 may be attractive drug targets for therapeutic interventions in TDP-43 proteinopathies such as FTLD-TDP and ALS.(PMID:25473830).
