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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

TXNL6 Polyclonal antibody, PBS Only

TXNL6 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11203-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse brain tissue using TXNL6 Polyclonal antibody (11203-1-AP)

    WB analysis of mouse brain using 11203-1-AP (same clone as 11203-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 11203-1-AP (TXNL6 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11203-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using TXNL6 Polyclonal antibody (11203-1-AP)

    WB analysis of HeLa using 11203-1-AP (same clone as 11203-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 11203-1-AP (TXNL6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11203-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse brain tissue using TXNL6 Polyclonal antibody (11203-1-AP)

    IP experiment of mouse brain using 11203-1-AP (same clone as 11203-1-PBS)

    IP result of anti-TXNL6 (IP:11203-1-AP, 4ug; Detection:11203-1-AP 1:500) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 11203-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using TXNL6 Polyclonal antibody (11203-1-AP)

    IHC staining of human breast cancer using 11203-1-AP (same clone as 11203-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11203-1-AP (TXNL6 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 11203-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using TXNL6 Polyclonal antibody (11203-1-AP)

    IHC staining of human breast cancer using 11203-1-AP (same clone as 11203-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 11203-1-AP (TXNL6 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11203-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using TXNL6 Polyclonal antibody (11203-1-AP)

    IHC staining of human breast cancer using 11203-1-AP (same clone as 11203-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 11203-1-AP (TXNL6 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11203-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

11203-1-PBS targets TXNL6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TXNL6 fusion protein Ag1691 相同性解析による交差性が予測される生物種
Full Name nucleoredoxin-like 1
Calculated molecular weight 24 kDa
Observed molecular weight 26-28 kDa
GenBank accession numberBC014127
Gene symbol NXNL1
Gene ID (NCBI) 115861
RRIDAB_2158126
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TXNL6, also named as NXNL1, belongs to the nucleoredoxin family. It may play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods. TXNL6 is a Novel Oxidative Stress-Induced Reducing System for Methionine Sulfoxide Reductase A Repair of a-Crystallin and Cytochrome C in the Eye Lens. It serve as a reducing system for MsrA repair of the essential lens chaperone a-crystallin/sHSP and mitochondrial cytochrome c. TXNL6 is induced at high levels in human lens epithelial cells exposed to H2O2-induced oxidative stress.(PMID:21079812)