- Featured Product
- KD/KO Validated
Thyroid Hormone Receptor beta Polyclonal antibody
Thyroid Hormone Receptor beta Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Mouse and More (2)
Applications
WB, IF, ELISA
Conjugate
Unconjugated
Cat no : 21007-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse retina tissue, mouse eye tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
| IF | See 1 publications below |
Product Information
21007-1-AP targets Thyroid Hormone Receptor beta in WB, IF, ELISA applications and shows reactivity with Mouse samples.
| Tested Reactivity | Mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Thyroid Hormone Receptor beta fusion protein Ag15210 相同性解析による交差性が予測される生物種 |
| Full Name | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) |
| Calculated molecular weight | 476 aa, 54 kDa |
| Observed molecular weight | 50 kDa |
| GenBank accession number | BC106929 |
| Gene symbol | Thyroid Hormone Receptor beta |
| Gene ID (NCBI) | 7068 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Thyroid hormone receptor beta (THRB), also known as ERBA2, NR1A2, and THR1, belongs to the nuclear hormone receptor family and NR1 subfamily. THRB is a nuclear hormone receptor that can act as a repressor or activator of transcription. Moreover, THRB is also a high-affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. THRB is the most abundant THR isoform in the liver but is also expressed in other tissues and mediates the effects of THs on hepatic carbohydrate and lipid metabolism (PMID: 34884910).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Thyroid Hormone Receptor beta antibody 21007-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Theranostics Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease
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