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U2AF35 Monoclonal antibody, PBS Only

U2AF35 Monoclonal Antibody for WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA
Cat No. 60289-1-PBS
Clone No.2B7F11

Host / Isotype

Mouse / IgG2c

Reactivity

rat, mouse, human

Applications

WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA

U2AF1, U2AFBP, RNU2AF1, RN, FP793

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

60289-1-PBS targets U2AF35 in WB, IHC, IF/ICC, FC (Intra), IP, Indirect ELISA applications and shows reactivity with rat, mouse, human samples.

Tested Reactivity rat, mouse, human
Host / Isotype Mouse / IgG2c
Class Monoclonal
Type Antibody
Immunogen U2AF35 fusion protein Ag0399 相同性解析による交差性が予測される生物種
Full Name U2 small nuclear RNA auxiliary factor 1
Calculated molecular weight 28 kDa
Observed molecular weight 35-40 kDa
GenBank accession numberBC001923
Gene Symbol U2AF1
Gene ID (NCBI) 7307
RRIDAB_2858277
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ01081
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder. The calculated molecular weight of U2AF35 is 28 kDa, but the modified U2AF35 protein is about 35-40 kDa.

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