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CoraLite®647-conjugated U2AF35 Monoclonal antibody

U2AF35 Monoclonal Antibody for
Cat No. CL650-60289
Clone No.2B7F11

Host / Isotype

Mouse / IgG2c

Reactivity

human, mouse, rat

Applications

DKFZp313J1712, FP793, RN, RNU2AF1, U2AF1, U2AF35, U2AFBP

Formulation:  PBS and Azide
PBS and Azide
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL650-60289 targets U2AF35 in applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2c
Class Monoclonal
Type Antibody
Immunogen U2AF35 fusion protein Ag0399 相同性解析による交差性が予測される生物種
Full Name U2 small nuclear RNA auxiliary factor 1
Calculated molecular weight 28 kDa
Observed molecular weight 35-40 kDa
GenBank accession numberBC001923
Gene Symbol U2AF1
Gene ID (NCBI) 7307
Conjugate CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission maxima wavelengths654 nm / 674 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ01081
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder. The calculated molecular weight of U2AF35 is 28 kDa, but the modified U2AF35 protein is about 35-40 kDa.

Protocols

Product Specific Protocols
FC protocol for CL Plus 647 U2AF35 antibody CL650-60289Download protocol
Standard Protocols
Click here to view our Standard Protocols
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