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UGP2 Polyclonal antibody

UGP2 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 10391-1-AP

Synonyms

pHC379, UDP glucose pyrophosphorylase, UDPG, UDPGP, UDPGP2, UGP1, UGP2, UGPase, UGPP2


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Tested Applications

Positive WB detected inHepG2 cells, mouse liver tissue, HeLa cells, HEK-293 cells, rat liver tissue
Positive IHC detected inhuman ovary tumor tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10391-1-AP targets UGP2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen UGP2 fusion protein Ag0590 相同性解析による交差性が予測される生物種
Full Name UDP-glucose pyrophosphorylase 2
Calculated molecular weight 56 kDa
Observed molecular weight 50-56 kDa
GenBank accession numberBC002954
Gene symbol UGP2
Gene ID (NCBI) 7360
RRIDAB_2272775
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

UDP-glucose pyrophosphorylase 2 (UGP2, synonyms: UDPG, UGPP2, UDPGP2, Phc379)is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. So far two isoforms are encoded by two transcript variants have been found.

Protocols

Product Specific Protocols
WB protocol for UGP2 antibody 10391-1-APDownload protocol
IHC protocol for UGP2 antibody 10391-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

iScience

MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.

Authors - Dong-Xue Ding
ratIHC

Toxicol Sci

Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis.

Authors - Kakehashi Anna A
humanIHC

Dis Markers

Low UGP2 Expression Is Associated with Tumour Progression and Predicts Poor Prognosis in Hepatocellular Carcinoma.

Authors - Qiuyue Hu
humanWB

J Cell Biochem

Identification of UGP2 as a progression marker that promotes cell growth and motility in human glioma.

Authors - Chun Zeng
  • KD Validated