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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

UPK1B Polyclonal antibody, PBS Only

UPK1B Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 26853-1-PBS

Synonyms

Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of human urothelial carcinoma tissue using UPK1B Polyclonal antibody (26853-1-AP)

    IHC staining of human urothelial carcinoma using 26853-1-AP (same clone as 26853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 26853-1-AP (UPK1B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26853-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human urothelial carcinoma tissue using UPK1B Polyclonal antibody (26853-1-AP)

    IHC staining of human urothelial carcinoma using 26853-1-AP (same clone as 26853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 26853-1-AP (UPK1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26853-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse bladder tissue using UPK1B Polyclonal antibody (26853-1-AP)

    IHC staining of mouse bladder using 26853-1-AP (same clone as 26853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 26853-1-AP (UPK1B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26853-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse bladder tissue using UPK1B Polyclonal antibody (26853-1-AP)

    IHC staining of mouse bladder using 26853-1-AP (same clone as 26853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 26853-1-AP (UPK1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26853-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

26853-1-PBS targets UPK1B in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen UPK1B fusion protein Ag25471 相同性解析による交差性が予測される生物種
Full Name uroplakin 1B
GenBank accession numberBC063568
Gene symbol UPK1B
Gene ID (NCBI) 7348
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-1B (UPK1B) belongs to the tetraspanin (TM4SF) family. UPK1B can promote the proliferation, invasion and metastasis of tumor cells and regulate the development and progression of tumors (PMID: 30229818).