Validation Data Gallery
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Tested Applications
| Positive WB detected in | COLO 320 cells, HepG2 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
23984-1-AP targets UTX in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | UTX fusion protein Ag20018 相同性解析による交差性が予測される生物種 |
| Full Name | ubiquitously transcribed tetratricopeptide repeat, X chromosome |
| Calculated molecular weight | 1401 aa, 154 kDa |
| Observed molecular weight | 154 kDa |
| GenBank accession number | BC093868 |
| Gene Symbol | UTX |
| Gene ID (NCBI) | 7403 |
| RRID | AB_2935460 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O15550 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
KDM6A, also named UTX, mediates the removal of repressive trimethylation of histone H3, it plays a central role in the regulation of posterior development, by regulating HOX gene expression (PubMed:17851529).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for UTX antibody 23984-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Eur J Med Res Inactivation of KDM6A promotes the progression of colorectal cancer by enhancing the glycolysis |