Anti-Mouse VEVEGFR2/KDR Rabbit Recombinant Antibody, PBS Only
VEVEGFR2/KDR Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
mouse
Applications
FC
Conjugate
Unconjugated
CloneNo.
240214F12
Cat no : 98027-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
The immunogen of 98027-1-PBS is VEVEGFR2/KDR Fusion Protein expressed in E. coli.
| Tested Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Fusion Protein 相同性解析による交差性が予測される生物種 |
| Full Name | kinase insert domain protein receptor |
| Calculated molecular weight | 150KD |
| GenBank accession number | NM_010612.2 |
| Gene symbol | VEGFR-2 |
| Gene ID (NCBI) | 16542 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
VEGFR2, also named as CD309, KDR and FLK1, is a receptor for VEGF or VEGFC. VEGFR2 which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGFR2 functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
