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VEGFR2/KDR Monoclonal antibody, PBS Only

VEGFR2/KDR Monoclonal Antibody for WB, ELISA
Cat No. 67407-1-PBS
Clone No.1G2A8

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, ELISA

KDR, VEGFR2, Protein-tyrosine kinase receptor flk-1, FLK-1, EC:2.7.10.1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67407-1-PBS targets VEGFR2/KDR in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen VEGFR2/KDR fusion protein Ag24589 相同性解析による交差性が予測される生物種
Full Name kinase insert domain receptor (a type III receptor tyrosine kinase)
Calculated molecular weight 1356 aa, 152 kDa
Observed molecular weight 230 kDa
GenBank accession numberBC131822
Gene Symbol KDR
Gene ID (NCBI) 3791
RRIDAB_2882648
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP35968
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

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