WDR41 Polyclonal antibody
WDR41 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 26817-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | fetal human brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
26817-1-AP targets WDR41 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | WDR41 fusion protein Ag25275 相同性解析による交差性が予測される生物種 |
| Full Name | WD repeat domain 41 |
| Calculated molecular weight | 459 aa, 52 kDa |
| Observed molecular weight | 52 kDa |
| GenBank accession number | BC040241 |
| Gene symbol | WDR41 |
| Gene ID (NCBI) | 55255 |
| RRID | AB_2880646 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
WDR41, or WD40 repeat-containing protein 41, is a protein that plays a role in regulating cellular processes, particularly in the context of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). It is part of a complex that includes C9ORF72 and SMCR8, which has been shown to regulate autophagy and function as a Rab GTPase-activating protein (GAP). The C9ORF72-SMCR8-WDR41 complex is believed to participate in the regulation of membrane trafficking and autophagy-lysosome pathway.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for WDR41 antibody 26817-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Acta Neuropathol Commun C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease. |
