WWOX Monoclonal antibody, PBS Only
WWOX Monoclonal Antibody for WB, IHC, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, rat, pig, mouse
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
1B8F4
Cat no : 67725-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67725-1-PBS targets WWOX in WB, IHC, ELISA applications and shows reactivity with Human, rat, pig, mouse samples.
Tested Reactivity | Human, rat, pig, mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | WWOX fusion protein Ag7969 相同性解析による交差性が予測される生物種 |
Full Name | WW domain containing oxidoreductase |
Calculated molecular weight | 47 kDa |
Observed molecular weight | 40 kDa |
GenBank accession number | BC003184 |
Gene symbol | WWOX |
Gene ID (NCBI) | 51741 |
RRID | AB_2882911 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
WWOX(WW domain-containing oxidoreductase) is also named as FOR, WOX1 and belongs to the short-chain dehydrogenases/reductases (SDR) family. The gene encodes a 46 kDa protein that contains two WW domains and a short-chain dehydrogenase/reductase domain and the protein is lost or reduced in the majority of many cancer types including breast, prostate, esophageal, lung, stomach, and pancreatic carcinomas and in a large fraction of other cancer types(PMID:17360458). WWOX behaves as a potential tumor-suppressor gene(PMID:15064722). It has 7 isoforms produced by alternative splicing.